PUBLICATIONS

 

A family of endonucleases blocks nanotube-mediated plasmid exchange. 

Gopu et al,  2026
Nat. Microbiol. 11(4):960-975.

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Flagellar rotation facilitates the transfer of a bacterial conjugative plasmid 

Bhattacharya S, Bejerano-Sagie M, Ravins M, Zeroni L, Kaur P, Gopu V, Rosenshine I, Ben-Yehuda S. 2025,EMBO J.  Jan;44(2):587-61100320-0. Epub 2024 Dec 2.PMID: 39623141

 

The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop, Gur-Arie et al., 2020, J Biol Chem doi: 10.1074/jbc.RA120.013590

 

A Ubiquitous Platform for Bacterial Nanotube Biogenesis.

Bhattacharya S, Baidya AK, Pal RR, Mamou G, Gatt YE, Margalit H, Rosenshine I, Ben-Yehuda S. 2019, Cell Reports, 27:334-342.

Host-cell attachment elicits post-transcriptional regulation in infecting enteropathogenic bacteria.

Katsowich N., Elbaz N., Pal RP., Mills M., Kobi S., Kahan T and Ilan Rosenshine 2017, Science, 355(6326):735-739

 

The Type III secretion effector NleE inhibits NF-κB activation.

Nadler C., Baruch K., Kobi S., Mills E., Farago M., Alkalay I., Bartfeld S., Meyer T. F., Ben-Neriah Y., and Rosenshine I. 2010, PLOS Pathogens, 6: e100074

 

A Bifunctional T3SS-Effector Simultaneously Cleaves Host MAP Kinase and Inhibits PPM1A Phosphatase

Socol et al., 2026, Adv Sci . 28:e09702.

 

Activation of the Type III Secretion System of Enteropathogenic Escherichia coli Leads to Remodeling of Its Membrane Composition and Function   Zacharia et al., (2022) mSystems 7:e00202-22 

 

Donor-delivered cell wall hydrolases facilitate nanotube penetration into recipient bacteria. Baidya AK, Rosenshine I, Ben-Yehuda S
2020, Nature Commun, 11(1):1938. doi: 10.1038/s41467-020-15605-1.
nature.com

 

Pathogenic E. coli Extracts Nutrients from Infected Host Cells Utilizing Injectisome Components.

Pal RR, Baidya AK, Mamou G, Bhattacharya S, Socol Y, Kobi S, Katsowich N, Ben-Yehuda S, Rosenshine I. 2019, Cell. 177:683-696

 

Dynamics of expression and maturation of the type III secretion system of enteropathogenic Escherichia coli.

Yerushalmi G., Gur-Arie L., Litvak Y., and Rosenshine I. 2014, J. Bacteriol. 196:2798-2806.

 

Uncovering phenotypic inheritance from single cells with Microcolony-seq.
Faigenbaum-Romm R, Yedidi N, Gefen O, Katsowich-Nagar N, Aroeti L, Ronin I, Bar-Meir M, Rosenshine I*, Balaban NQ*. 2025 Cell,;188(19):5313-5331.

 

The impact of Hfq-mediated sRNA-mRNA interactome on the virulence of enteropathogenic Escherichia coli. Pearl Mizrahi et al., 2021, Science Advances, doi:  10.1126/sciadv.abi8228

 

Control of type III secretion system effector/chaperone ratio fosters pathogen adaptation to host adherent lifestyle.

Elbaz N., Socol Y., Katsowich N. and I Rosenshine.

2019, mBio, 17;10(5). pii: e02074-19

Epithelial cells detect functional type III secretion system of enteropathogenic Escherichia coli through a novel NF-κB signaling pathway.

Litvak Y., Sharon S., Hyams M., Zhang L., Kobi S., Katsowich N., Dishon S., Nussbaum G., Dong N., Shao F. and Rosenshine I. 2017, PLOS Pathogens 13(7):e1006472

 

The dynamics of the type III secretion system activity of enteropathogenic E. coli

Mills E., Baruch K., Aviv G., Nitzan M. and Rosenshine I. 2013, mBio 4:e00303-13.

 

Formation of a membraneless compartment regulates bacterial virulence
Aroeti et al., 2025
Nat Commun. 16(1):3834.​

 

Binding specificity of type three secretion system effector NleH2 to multi-cargo chaperone CesT and their phosphorylation Yadav et al., 2021, J. Protein Sci. doi: 10.1002/pro.4210. n

 

Pathogenic E. coli Extracts Nutrients from Infected Host Cells Utilizing Injectisome Components.
Pal et al., 2019.
Cell, 77(3):683-696.

A Long-term Epigenetic Memory Switch Controls Bacterial Virulence Bimodality.

Ronin I., Katsowich N., Rosenshine I., and Balaban N., 2017, eLife, e19599. doi: 10.7554/eLife.19599

Metalloprotease Type III effectors that specifically cleave

Baruch K., Gur-Arie L., Nadler C., Koby S., Yerushalmi G., Ben-Neriah Y., Yogev O., Shaulian E., Guttman C., Zarivach R., and Rosenshine I., 2011, JNK and NF-κB. EMBO J. 30:221-231.